![]() Including a section on macromolecules, that will tell you the names of the protein chains and how many protein chains there are in the protein. Macromoleculesĭon't panic, though, the 2HIU file PDB page can also provide you with lots of other information. If you want more information on how to read scientific journal articles, check out the three pass approach. The idea is to get the big picture about the structure of the molecule. When reading a scientific journal article for the first time, you do not need to understand every single word. In addition, we recommend looking at all of the figures. We recommend reading the abstract, introduction, and discussion. While parts of the article may be difficult for you to read, it can be a great source of information for you. ![]() The Literature section will provide you with the primary citation. LiteratureĪ great place to start finding information about your molecule is the Literature section of the 2HIU PDB page ( ). Find the resolution on the 2HIU pdb page. What is the resolution of our 2HIU file? 3. the higher the resolution of the structure, the greater the uncertainty in the structure of the model.ġ. Lower resolution structures (greater than or equal to 3 angstroms) show only the basic contours of the protein chain, and the atomic structure must be inferred. High-resolution structures (less than or equal to 1 angstrom) are highly ordered and it is easy to see every atom in the electron density map. Essentially, resolution is a measure of the level of detail present in the structure. Resolution is a measure of the quality of the data that has been collected on the crystal containing the protein. Let's see if we can find the following information:ġ) What is this structure classified as (see "classification')? What does this mean about the function of this molecule?Ģ) What organism is this protein from? 2. This page has some valuable information about the structure. When you get to this page, it will look like the page below. You can enter this into the search bar on the Protein Data Bank or follow the link below: For human insulin the file identifier is 2HIU. Įach file in the protein data bank has a four letter/number identifier. The protein data bank is a repository of 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand structure function relationships. Below is a process you can follow to create your own molecular stories. Then, you will have an opportunity to explore and create a molecular story with a Penn State research mentor. ![]() During the first part of the workshop, we will guide you through the molecular story of insulin. During this workshop, we will be guiding you through how to create and explore a molecular story with your students. We recommend doing this through the creation of molecular stories. The protein data bank is an excellent resource for you and your students to explore structure and function relationships.
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